Friday, May 15, 2020

An Evaluation Of The Nih Clinical Trial Registry - 1777 Words

Introduction The number of older individuals undergoing HSCT for malignant disease has risen considerably over the years. Between 2007- 2013, 22% of allogeneic transplants and 44% of autologous transplants were in patients older than 60 years of age1. The rise of HSCT in this age group can be attributed to the use of reduced intensity conditioning (RIC) regimen and advances in post-HSCT supportive care2,3. HSCT is a potential curative treatment for a number of malignant hematologic diseases such as myelodysplastic syndrome (MDS), leukemia, lymphoma and myeloma which tend to more commonly affect the elderly population. For instance, according to the SEER database, the median age of diagnosis of acute myeloid leukemia (AML) and MDS are 67 and 70 years respectively. Despite these findings, the number of patients over the age of 65 undergoing allogeneic HSCT remains low4. An evaluation of the NIH clinical trial registry revealed that 90% of HSCT clinical trials excluded older individuals (75 years), 75% based on chronologic age, 39% based on performance status in the elderly and 39% based on organ function in the elderly5. Inadequate accrual remains a problem even for trials that allow older patients, mostly due to physician reluctance, comorbidities and performance status6. Low rates of HSCT in the elderly and poor enrollment in HSCT clinical trials appear to be due to concerns regarding certain patient factors. Increasing age is associated with higher incidence of comorbidShow MoreRelatedStudy On Breast Cancer Management Guidelines Essay1584 Words   |  7 PagesMANAGEMENT GUIDELINES ABSTRACT- Cancer is a big cause of death worldwide. Around the world Cancer of different types effect millions of population and leads to loss of lives. According to the available data through our complete and thorough nationwide registries on cancer (number of times something happens), number and death in India among males cancers of lung, mouth, oesophagus and stomach are leading places/locations of cancer and among females cancer of breast, cervix are leading places/locations. BooksRead MoreA Brief Note On Lou Gehrig, The Greatest New York Yankee Baseball1967 Words   |  8 Pagesfor ubiquitin, and TAR DNA-binding protein (TDP-43). These inclusions lead to cell dysfunction and apoptosis (cell death). At autopsy the dorsal lateral spinal cord is gliotic and sclerotic; hence, lateral sclerosis (Ricks, 2005). Symptoms/ Clinical Features The Onset of ALS varies in anatomic location but disease progression is constant and linear. Changes are noted on a weekly or monthly basis. Many patients initially present with complaints of subtle focal weakness, stiff musclesRead MoreMedicare Policy Analysis447966 Words   |  1792 Pages089200 PO 00000 Frm 00064 Fmt 6652 Sfmt 6201 E:\BILLS\H3962.IH H3962 65 1 and emerging research and careful sci- 2 entific reviews, including the Guide to 3 Community 4 Guide to Clinical Preventative Services, 5 and the National Registry for Effective 6 Programs, and Preventative Services, the 7 (iii) includes strategies which focus on 8 prevention and support for employee popu- 9 lations at risk of poor health outcomes

Wednesday, May 6, 2020

The End Of The Holocaust - 1607 Words

Respect the Constitution 1945. The end of the Holocaust. Total death: 6 million Jews. As tragic as it was, there was only one person behind it all; Adolf Hitler. Hitler, the dictator during the time, managed to transform peaceful and normal people into extreme haters towards the Jews. 158 years earlier, a man had introduced ideas that could have prevented these 6 million Jews from dying. That man was James Madison, also known as the Father of the US Constitution. In Philadelphia’s summer heat of 1787, James Madison along with 55 other delegates attended to what is now known as the Constitutional Convention. The meeting was held to discuss their loose federal government, or known as The Articles of Confederation. The Articles of Confederation was a failure as it was too weak to unite a whole nation. The delegates thought that they must frame, or build a new government soon to be called the Constitution. The delegates were cautious about avoiding tyranny, or when harsh and absolute power gets in the han ds of one or a group of individuals. The Constitution guarded the nation against tyranny through federalism, separation of powers, checks and balances, and small/large state compromises. To start with, federalism was the first step framers took to secure the country from tyranny. As James Madison stated, â€Å"power surrendered by the people is first divided between two distinct governments†¦distinct and separate documents.† Madison made a new compound republic for America, known asShow MoreRelatedWhy Did The Holocaust End?878 Words   |  4 PagesLiberation of the Holocaust was a very joyful, yet devastating time period for the Jews and others that were under control of the Nazi forces. It was their release from a long imprisonment, but also the time that they realized that some of their most loved ones had not survived. The Jews went through excruciating pain during the time of the Holocaust. And proven by facts, many to most Jews did not make it to the end. The Holocaust, according to Merriam-Webster, is defined as, â€Å"the killing ofRead MoreHow did the holocaust end and what happened afterwards?1700 Words   |  7 PagesHow did the holocaust end and what happened afterwards? From 1933 onwards, Adolf Hitler and his Nazis began implementing simple discrimination laws against the Jews and others who they did not see part of their master race. Hitler and the Nazis believed that German power was being taken by the Jews. Hitler was able to convince his followers of this issue with the Jewish question as it was known, and get away with murdering millions of people in an attempt to cleanse society of anyone inferior toRead MoreA Different View of World War Two: Global Territory and the end of the Holocaust1173 Words   |  5 Pagessecuring global territory. In addition this essay will attempt to demonstrate that the generally accepted views of World War Two do not accurately represent what actually happened during the war by presenting evidence that suggests that ending the holocaust was not considered a priority by the political leaders of the allied powers. In the years leading up to World War Two, world domination in terms of landmass and population had largely been secured by the Allied powers. The term allied powers refersRead MoreSenderS Profile Photofrank E. Smart. Holocaust Essay.1023 Words   |  5 Pages Sender s profile photo Frank E. Smart Holocaust Essay Mr. Grosse Feb 9 The Holocaust The Holocaust was the state-sponsored persecution also murder 6 Million Jews by the Nazi regimes. holocaust is also a Greek word meaning â€Å"Sacrifice by Fire†. The Nazi came in power in Germany in January 1933. They all believed that Germans was â€Å"Superior† and that the Jews, were also alien threating to call German racial community. In 1933, The Jewish population of Europe they all stood over nine millionRead MoreNever to forget1710 Words   |  7 PagesThe book I read was Never To Forget The Jews of the Holocaust by Milton Meltzer. The book is written by Meltzer’s true story of the. It tells the story of when over five million Jewish people were massacred. The book has no characters. From beginning to end the book takes place in Germany. It only tells the straight forward account of the Jewish Holocaust. He writes the story in an interesting view point because he is an old American Jew, watching events of the war from newspapers and radios. WritingRea d MoreThe Holocausts Effect on the German Jew Essay1745 Words   |  7 Pagesaction his plan of elimination. This is not only why German Jews were the main target of the Holocaust, but why they were a large part of the years before, during, and after the Holocaust. Hitler’s â€Å"final solution† almost eliminated the Jewish population in Europe during World War II. At the end of the war and along with his suicide, the Jewish population would survive the horror known as the Holocaust and the Jews would eventually find their way back to their homeland of Israel as well as findRead MoreThe Holocaust And The Nazi War1011 Words   |  5 PagesThe Holocaust The Holocaust was the state-sponsored persecution also murder 6 Million Jews by the Nazi regimes. holocaust is also a Greek word meaning â€Å"Sacrifice by Fire†. The Nazi came in power in Germany in January 1933. They all believed that Germans was â€Å"Superior† and that the Jews, were also alien threating to call German racial community. In 1933, The Jewish population of Europe they all stood over nine million. The Jews lived in the countries that Nazi Germany would occupy of the influenceRead More`` Maus `` By Art Spiegelman And The 1997 Film Of Life Is Beautiful1557 Words   |  7 Pagesthe Holocaust. Maus, although presented as a graphic novel, strongly depicts the story of Vladek, a Holocaust survivor through his son’s recollection of the unfortunate events that occurred to him while evidently containing a torn relationship due to the effects of surviving one of the most tragic events in history. Whereas the film, Life is Beautiful portrays the tale of a Jewish family told by the forever appreciate son, Joshua, of Guido who creatively distorted the reality of the Holocaust to preserveRead MoreLasting Effects of the Holocaust1195 Words   |  5 PagesThe Holocaust not only affected the areas where it took place, it affected the entire world. Even though Jewish people were the main victims in the Holocaust, it also left lasting effects on other groups of people. Both the Nazi and Jewish decedents still feel the aftermath of one of the most horrific counts of genocide that the world has ever encountered. The cries of the victims in concentration camps still ring around the globe today, and they are not easily ignored. Although the Holocaust tookRead MoreThe On Coping With The Holocaust Experience1401 Words   |  6 Pagesthrown into chaos because of the Holocaust. Families were ripped apart and values were washed away as citizens were forcefully placed in concentration camps to either be immediately killed or to work until they d ied. Every person within the camps faced unthinkable trauma. Once everyone was released, the prisoners began to search for lost loved ones and a sense of normality. However, the anguish did not end with the end of the Holocaust. Following the Holocaust, first generation survivors developed

Tuesday, May 5, 2020

Chinese Calligraphy, Painting and History Essay Example For Students

Chinese Calligraphy, Painting and History Essay In contrast to western calligraphy, diffusing ink blots ND dry brush strokes are viewed as a natural impromptu expression rather than a fault. While western calligraphy often pursue font-like uniformity, homogeneity of characters in one size is only a craft. To the artist, calligraphy is a mental exercise that coordinates the mind and the body to choose the best styling in expressing the content of the passage. It is a most relaxing yet highly disciplined exercise indeed for ones physical and spiritual bevel being. Historically, many calligraphy artists were well-known for their longevity. Brush calligraphy is not only loved and practiced by Chinese. Koreans and Japanese equally adore calligraphy as an important treasure Of their heritage. Many Japanese schools still have the tradition of having a student contest of writing big characters during beginning of a new school year. A biannual gathering commemorating the Lancing Xx by Wang Xi Chi (The most famous Chinese calligrapher in Jinn dynasty, ) is said to be held ceremonially in Japan. There is a national award of Wang Xi Chi prize for the best calligraphy artist, Not too long ago, Korean government officials were required to excel in calligraphy. The office of Okinawa governor still displays a large screen of Chinese calligraphy s a dominating decor. In the West, Picasso and Matisse are two artists who openly declared the influence by Chinese calligraphy on their works, Easier Calligraphy is the art of making beautiful or elegant handwriting. It is a fine art of skilled penmanship. Harder The word calligraphy literally means beautiful writing. Before the invention Of the printing press some 500 years ago, it was the way books were made. Each copy was handwritten out by a scribe working in a scriptorium. The hand writing was done With quill and ink onto materials like vellum or parchment. The lettering style applied was one of the period backhands like cutis, Carolingian, blacklisted, etc. Today, there are three main types or styles of calligraphy: (1) Western or Roman, (2) Arabic, and Chinese or Oriental. This project focuses mainly on Western calligraphy with a glimpse at the other two styles. topic Wang Xiii ?-t ± Wang Xiii is a Chinese calligrapher. He is considered by some as the first artist in the Western sense, insofar as it has moved away from the official canon in force, the cursive handwriting, practicing a form of free personal and pictorial practice. AU, Tastes, CENT,  ±Zip-F-If-E, ?i#-F-a, 4th-Y-